Marine Alkylpurines: A Promising Group of Bioactive Marine Natural Products

Marine Alkylpurines: A Promising Group of Bioactive Marine Natural Products †

Marine secondary metabolites with a purine motif in their structure are presented in this review. The alkylpurines are grouped according to the size of the alkyl substituents and their location on the purine ring. Aspects related to the marine source, chemical structure and biological properties are considered together with synthetic approaches towards the natural products and bioactive analogu...

Bioactive marine natural products

Bioactive marine natural products can be defined as biologically active products, both secondary metabolites as well as enzymes, lipids and heteropolysaccharides derived from marine sources. Marine natural products have been found to be an important source of drugs and drug leads. These natural products are secondary metabolites and enhance survival fitness and may serve as chemical weapons use...

marine microbial natural products

Bioactive Natural Products of Marine Sponges from the Genus Hyrtios.

Marine sponges are known as a rich source for novel bioactive compounds with valuable pharmacological potential. One of the most predominant sponge genera is Hyrtios, reported to have various species such as Hyrtios erectus, Hyrtios reticulatus, Hyrtios gumminae, Hyrtios communis, and Hyrtios tubulatus and a number of undescribed species. Members of the genus Hyrtios are a rich source of natura...

Examination of Marine-Based Cultivation of Three Demosponges for Acquiring Bioactive Marine Natural Products

Marine sponges are an extremely rich and important source of natural products. Mariculture is one solution to the so-called "supply problem" that often hampers further studies and development of novel compounds from sponges. We report the extended culture (767 days) at sea in depths of 10 and 20 m of three sponge species: Negombata magnifica, Amphimedon chloros and Theonella swinhoei that produ...